The field of macrophage research has grown enormously since publication of the first edition of this book. The Macrophage 2e provides a unique comprehensive review of the current scientific knowledge of the multifaceted role of this important and intriguiging cell in health and disease. In 16 chapters by experts in the field it covers the basic biology and diverse functions of macrophages in specific diseases and the complex of interactions between macrophages and other cells. Ranging from their role in the defense against pathogens, their role as hosts for pathogens (including HIV), their complex roles in diseases such as arthritis and cancer, and their potential for use in novel gene therapy approaches to disease treatment, the book gives an up to the minute account of active macrophage research. The editors have intentionally included a broad rangeof topics that will appeal not only to immunologists and cell biologists but will also be of interest to those working in the specific disease areas covered.